Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Research Publications


Publications for Liam Heaney

From (year): To (year):

Download all publications as Word document


Journal Articles

Salzano, A, D’Assante, R, Iacoviello, M, Triggiani, V, Rengo, G, Cacciatore, F, Maiello, C, Limongelli, G, Masarone, D, Sciacqua, A, Filardi, PP, Mancini, A, Volterrani, M, Vriz, O, Castello, R, Passantino, A, Campo, M, Modesti, PA, De Giorgi, A, Arcopinto, M, Gargiulo, P, Perticone, M, Colao, A, Milano, S, Garavaglia, A, Napoli, R, Suzuki, T, Bossone, E, Marra, AM, Cittadini, A, Heaney, L (2022) Progressive right ventricular dysfunction and exercise impairment in patients with heart failure and diabetes mellitus: insights from the T.O.S.CA. Registry, Cardiovascular Diabetology, 21(1), 108, DOI: 10.1186/s12933-022-01543-3.

De Giorgi, A, Marra, AM, Iacoviello, M, Triggiani, V, Rengo, G, Cacciatore, F, Maiello, C, Limongelli, G, Masarone, D, Perticone, F, Filardi, PP, Paolillo, S, Mancini, A, Volterrani, M, Vriz, O, Castello, R, Passantino, A, Campo, M, Modesti, PA, Salzano, A, D’Assante, R, Arcopinto, M, Raparelli, V, Fabbian, F, Sciacqua, A, Colao, A, Suzuki, T, Bossone, E, Cittadini, A, Saccà, L, Monti, MG, Napoli, R, Matarazzo, M, Stagnaro, FM, Schiavo, A, Valente, P, Ferrara, F, Russo, V, Malinconico, M, Citro, R, Guastalamacchia, E, Leone, M, Amarelli, C, Mattucci, I, Calabrò, P, Calabrò, R, D’Andrea, A, Maddaloni, V, Pacileo, G, Scarafile, R, Belfiore, A, Cimellaro, A, Casaretti, L, Gargiulo, P, Favuzzi, AMR, Segni, CD, Bruno, C, Vergani, E, Frigo, A, Sorrentino, MR, Malandrino, D, Manfredini, R, Puzzo, A, Ragusa, L, Caliendo, L, Carbone, L, Frigiola, A, Generali, T, Giacomazzi, F, De Vincentiis, C, Ballotta, A, Garofalo, P, Malizia, G, Heaney, L, Bruzzese, D (2022) Insulin-like growth factor-1 (IGF-1) as predictor of cardiovascular mortality in heart failure patients: data from the T.O.S.CA. registry, Internal and Emergency Medicine, ISSN: 1828-0447. DOI: 10.1007/s11739-022-02980-4.

Rankin-Turner, S, Reynolds, J, Turner, M, Heaney, L (2022) Applications of ambient ionization mass spectrometry in 2021: An annual review, Analytical Science Advances, 3(3-4), pp.67-89, DOI: 10.1002/ansa.202100067.

Heaney, L, Kang, S, Turner, M, Lindley, M, Thomas, P (2022) The impact of a graded maximal exercise protocol on exhaled volatile organic compounds: a pilot study, Molecules, 27(2), 370, DOI: 10.3390/molecules27020370.

Annese, VF, Patil, SB, Hu, C, Giagkoulovits, C, Al-Rawhani, MA, Grant, J, Macleod, M, Clayton, DJ, Heaney, LM, Daly, R, Accarino, C, Shah, YD, Cheah, BC, Beeley, J, Evans, TRJ, Jones, R, Barrett, MP, Cumming, DRS (2021) A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection, Microsystems and Nanoengineering, 7(1), DOI: 10.1038/s41378-021-00243-4.

Bongiovanni, T, Ong, MLY, Heaney, L (2021) The Athlete and Gut Microbiome: Short-chain Fatty Acids as Potential Ergogenic Aids for Exercise and Training, International Journal of Sports Medicine, 42(13), pp.1143-1158, ISSN: 0172-4622. DOI: 10.1055/a-1524-2095.

Bongiovanni, T, Yin, MOL, Heaney, LM (2021) Erratum: Correction: The Athlete and Gut Microbiome: Short-chain Fatty Acids as Potential Ergogenic Aids for Exercise and Training (International journal of sports medicine (2021) 42 13 (1143-1158), International journal of sports medicine, 42(13), e1, DOI: 10.1055/a-1737-0736.

Hatcher, CR, Sommer, U, Heaney, LM, Millett, J (2021) Metabolomic analysis reveals reliance on secondary plant metabolites to facilitate carnivory in the Cape sundew, Drosera capensis, Annals of Botany, 128(3), pp.301-314, ISSN: 0305-7364. DOI: 10.1093/aob/mcab065.

Man, K, Brunet, MY, Fernandez-Rhodes, M, Williams, S, Heaney, LM, Gethings, LA, Federici, A, Davies, OG, Hoey, D, Cox, SC (2021) Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast-derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation, J Extracell Vesicles, 10(9), e12118, ISSN: 2001-3078. DOI: 10.1002/jev2.12118.

Rankin-Turner, S, Vader, P, O'Driscoll, L, Giebel, B, Heaney, LM, Davies, OG (2021) A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos, Adv Drug Deliv Rev, 173, pp.479-491, DOI: 10.1016/j.addr.2021.04.012.

Israr, MZ, Bernieh, D, Salzano, A, Cassambai, S, Yazaki, Y, Heaney, LM, Jones, DJL, Ng, LL, Suzuki, T (2021) Association of gut-related metabolites with outcome in acute heart failure, Am Heart J, 234, pp.71-80, DOI: 10.1016/j.ahj.2021.01.006.

Rankin‐Turner, S and Heaney, LM (2021) Applications of ambient ionization mass spectrometry in 2020: An annual review, Analytical Science Advances, 2(3-4), pp.193-212, ISSN: 2628-5452. DOI: 10.1002/ansa.202000135.

Cittadini, A, Salzano, A, Iacoviello, M, Triggiani, V, Rengo, G, Cacciatore, F, Maiello, C, Limongelli, G, Masarone, D, Perticone, F, Cimellaro, A, Filardi, PP, Paolillo, S, Mancini, A, Volterrani, M, Vriz, O, Castello, R, Passantino, A, Campo, M, Modesti, PA, de Giorgi, A, Monte, IP, Puzzo, A, Ballotta, A, D’Assante, R, Arcopinto, M, Gargiulo, P, Sciacqua, A, Bruzzese, D, Colao, A, Napoli, R, Suzuki, T, Eagle, KA, Ventura, HO, Marra, AM, Bossone, E, Marra, AM, D’Assante, R, Saccà, L, Monti, MG, Matarazzo, M, Stagnaro, FM, Piccioli, L, Lombardi, A, Panicara, V, Flora, M, Golia, L, Faga, V, Ruocco, A, della Polla, D, Franco, R, Schiavo, A, Gigante, A, Spina, E, Sicuranza, M, Monaco, F, Apicella, M, Miele, C, Campanino, AG, Mazza, L, Abete, R, Farro, A, Luciano, F, Polizzi, R, Ferrillo, G, de Luca, M, Crisci, G, Giardino, F, Barbato, M, Ranieri, B, Bossone, E, Ferrara, F, Russo, V, Malinconico, M, Citro, R, Guastalamacchia, E, Leone, M, Giagulli, VA, Amarelli, C, Mattucci, I, Calabrò, P, Calabrò, R, D’Andrea, A, Maddaloni, V, Pacileo, G, Scarafile, R, Belfiore, A, Casaretti, L, Gargiulo, P, Favuzzi, AMR, Di Segni, C, Bruno, C, Vergani, E, Massaro, R, Grimaldi, F, Frigo, A, Sorrentino, MR, Malandrino, D (2021) Multiple hormonal and metabolic deficiency syndrome predicts outcome in heart failure: the T.O.S.CA. Registry, European Journal of Preventive Cardiology, 28(15), pp.1691-1700, ISSN: 2047-4873. DOI: 10.1093/eurjpc/zwab020.

Salzano, A, Israr, MZ, Yazaki, Y, Heaney, LM, Kanagala, P, Singh, A, Arnold, JR, Gulsin, GS, Squire, IB, McCann, GP, Ng, LL, Suzuki, T (2020) Combined use of trimethylamine N-oxide with BNP for risk stratification in heart failure with preserved ejection fraction: findings from the DIAMONDHFpEF study, Eur J Prev Cardiol, 27(19), pp.2159-2162, DOI: 10.1177/2047487319870355.

Yazaki, Y, Aizawa, K, Israr, MZ, Negishi, K, Salzano, A, Saitoh, Y, Kimura, N, Kono, K, Heaney, L, Cassambai, S, Bernieh, D, Lai, F, Imai, Y, Kario, K, Nagai, R, Ng, LL, Suzuki, T (2020) Ethnic differences in association of outcomes with trimethylamine N-oxide in acute heart failure patients, ESC Heart Fail, 7(5), pp.2373-2378, DOI: 10.1002/ehf2.12777.

Lippi, G and Heaney, LM (2020) The "olfactory fingerprint": can diagnostics be improved by combining canine and digital noses?, Clin Chem Lab Med, 58(6), pp.958-967, DOI: 10.1515/cclm-2019-1269.

Heaney, LM (2020) Advancements in mass spectrometry as a tool for clinical analysis: part II, Clin Chem Lab Med, 58(6), pp.855-857, DOI: 10.1515/cclm-2020-0259.

Henson, J, Edwardson, CL, Davies, MJ, Gill, JMR, Heaney, LM, Khunti, K, Ng, L, Sattar, N, Zaccardi, F, Yates, T (2020) Physical activity and lipidomics in a population at high risk of type 2 diabetes mellitus, J Sports Sci, 38(10), pp.1150-1160, DOI: 10.1080/02640414.2020.1744836.

Heaney, LM (2020) Applying mass spectrometry-based assays to explore gut microbial metabolism and associations with disease, Clin Chem Lab Med, 58(5), pp.719-732, DOI: 10.1515/cclm-2019-0974.

Heaney, LM (2020) Advancements in mass spectrometry as a tool for clinical analysis: Part I, Clin Chem Lab Med, 58(5), pp.639-642, DOI: 10.1515/cclm-2020-0199.

Heaney, LM, Kang, S, Turner, MA, Lindley, MR, Thomas, CLP (2020) Evidence for alternative exhaled elimination profiles of disinfection by-products and potential markers of airway responses to swimming in a chlorinated pool environment, Indoor Air, 30(2), pp.284-293, DOI: 10.1111/ina.12630.

Cassambai, S, Salzano, A, Yazaki, Y, Bernieh, D, Wong, M, Israr, MZ, Heaney, LM, Suzuki, T (2019) Impact of acute choline loading on circulating trimethylamine N-oxide levels, Eur J Prev Cardiol, 26(17), pp.1899-1902, DOI: 10.1177/2047487319831372.

Heaney, LM, Davies, OG, Selby, NM (2019) Gut microbial metabolites as mediators of renal disease: do short-chain fatty acids offer some hope?, Future Sci OA, 5(4), FSO384, ISSN: 2056-5623. DOI: 10.4155/fsoa-2019-0013.

Day, RL, Harper, AJ, Woods, RM, Davies, OG, Heaney, LM (2019) Probiotics: current landscape and future horizons, Future Sci OA, 5(4), FSO391, ISSN: 2056-5623. DOI: 10.4155/fsoa-2019-0004.

Heaney, LM and Martin, J (2019) Future Science OA 2019 early career researcher issue: foreword, Future Sci OA, 5(4), FSO393, ISSN: 2056-5623. DOI: 10.4155/fsoa-2019-0039.

Heaney, LM, Deighton, K, Suzuki, T (2019) Non-targeted metabolomics in sport and exercise science, J Sports Sci, 37(9), pp.959-967, DOI: 10.1080/02640414.2017.1305122.

Salzano, A, Marra, AM, Proietti, M, Raparelli, V, Heaney, LM (2019) Biomarkers in Heart Failure and Associated Diseases, Dis Markers, 2019, p.8768624, DOI: 10.1155/2019/8768624.

Davies, OG, Cox, SC, Azoidis, I, McGuinness, AJA, Cooke, M, Heaney, LM, Davis, ET, Jones, SW, Grover, LM (2019) Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies, Front Bioeng Biotechnol, 7, p.92, ISSN: 2296-4185. DOI: 10.3389/fbioe.2019.00092.

(2019) How to transition from 'early career' to 'established', Biotechniques, 66(1), pp.9-11, DOI: 10.2144/btn-2018-0182.

Davies, OG, Cox, SC, Azoidis, I, McGuinness, AJA, Cooke, M, Heaney, LM, Davis, ET, Jones, SW, Grover, LM (2019) Corrigendum: Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies, Front Bioeng Biotechnol, 7, p.392, ISSN: 2296-4185. DOI: 10.3389/fbioe.2019.00392.

Salzano, A, D'Assante, R, Heaney, LM, Monaco, F, Rengo, G, Valente, P, Pasquali, D, Bossone, E, Gianfrilli, D, Lenzi, A, Cittadini, A, Marra, AM, Napoli, R (2018) Klinefelter syndrome, insulin resistance, metabolic syndrome, and diabetes: review of literature and clinical perspectives, Endocrine, 61(2), pp.194-203, DOI: 10.1007/s12020-018-1584-6.

Salzano, A, Cittadini, A, Bossone, E, Suzuki, T, Heaney, LM (2018) Multiple hormone deficiency syndrome: a novel topic in chronic heart failure, Future Sci OA, 4(6), FSO311, ISSN: 2056-5623. DOI: 10.4155/fsoa-2018-0041.

Israr, MZ, Heaney, LM, Ng, LL, Suzuki, T (2018) B-type natriuretic peptide molecular forms for risk stratification and prediction of outcome after acute myocardial infarction, Am Heart J, 200, pp.37-43, DOI: 10.1016/j.ahj.2018.02.016.

Israr, MZ, Heaney, LM, Suzuki, T (2018) Proteomic Biomarkers of Heart Failure, Heart Fail Clin, 14(1), pp.93-107, ISSN: 1551-7136. DOI: 10.1016/j.hfc.2017.08.010.

Heaney, LM and Lindley, MR (2017) Translation of exhaled breath volatile analyses to sport and exercise applications, METABOLOMICS, 13(11), ARTN 139, ISSN: 1573-3882. DOI: 10.1007/s11306-017-1266-z.

Heaney, LM, Jones, DJ, Suzuki, T (2017) Mass spectrometry in medicine: a technology for the future?, Future Sci OA, 3(3), FSO213, ISSN: 2056-5623. DOI: 10.4155/fsoa-2017-0053.

Israr, MZ, Heaney, LM, Suzuki, T (2017) Serial measurements of natriuretic peptide to assess pharmacological interventions and subsequent impact on cardiovascular risk stratification in heart failure: a precision medicine approach, Journal of Laboratory and Precision Medicine, 2, pp.17-17, DOI: 10.21037/jlpm.2017.04.06.

Suzuki, T, Heaney, LM, Jones, DJL, Ng, LL (2017) In Reply, Clin Chem, 63(5), pp.1046-1047, DOI: 10.1373/clinchem.2017.272112.

Suzuki, T, Israr, MZ, Heaney, LM, Takaoka, M, Squire, IB, Ng, LL (2017) Prognostic Role of Molecular Forms of B-Type Natriuretic Peptide in Acute Heart Failure, Clin Chem, 63(4), pp.880-886, DOI: 10.1373/clinchem.2016.265140.

Suzuki, T, Heaney, LM, Jones, DJL, Ng, LL (2017) Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction (vol 63, pg 420, 2017), CLINICAL CHEMISTRY, 63(4), pp.926-926, ISSN: 0009-9147. DOI: 10.1373/clinchem.2017.271171.

Suzuki, T, Heaney, LM, Jones, DJL, Ng, LL (2017) Trimethylamine N-oxide and Risk Stratification after Acute Myocardial Infarction, Clin Chem, 63(1), pp.420-428, DOI: 10.1373/clinchem.2016.264853.

Israr, MZ, Heaney, LM, Suzuki, T (2017) In reply: The emerging value of molecular forms of B-type natriuretic peptide in heart failure, Journal of Laboratory and Precision Medicine, 2, pp.62-62, DOI: 10.21037/jlpm.2017.08.02.

Suzuki, T, Lyon, A, Saggar, R, Heaney, LM, Aizawa, K, Cittadini, A, Mauro, C, Citro, R, Limongelli, G, Ferrara, F, Vriz, O, Morley-Smith, A, Calabrò, P, Bossone, E (2016) Editor's Choice-Biomarkers of acute cardiovascular and pulmonary diseases, Eur Heart J Acute Cardiovasc Care, 5(5), pp.416-433, DOI: 10.1177/2048872616652309.

Mbasu, RJ, Heaney, LM, Molloy, BJ, Hughes, CJ, Ng, LL, Vissers, JPC, Langridge, JI, Jones, DJL (2016) Advances in quadrupole and time-of-flight mass spectrometry for peptide MRM based translational research analysis, Proteomics, 16(15-16), pp.2206-2220, DOI: 10.1002/pmic.201500500.

Heaney, LM, Ruszkiewicz, DM, Arthur, KL, Hadjithekli, A, Aldcroft, C, Lindley, MR, Thomas, CP, Turner, MA, Reynolds, JC (2016) Real-time monitoring of exhaled volatiles using atmospheric pressure chemical ionization on a compact mass spectrometer, Bioanalysis, 8(13), pp.1325-1336, DOI: 10.4155/bio-2016-0045.

Suzuki, T, Heaney, LM, Bhandari, SS, Jones, DJL, Ng, LL (2016) Trimethylamine N-oxide and prognosis in acute heart failure, Heart, 102(11), pp.841-848, DOI: 10.1136/heartjnl-2015-308826.

Heaney, LM, Jones, DJL, Mbasu, RJ, Ng, LL, Suzuki, T (2016) High mass accuracy assay for trimethylamine N-oxide using stable-isotope dilution with liquid chromatography coupled to orthogonal acceleration time of flight mass spectrometry with multiple reaction monitoring, Anal Bioanal Chem, 408(3), pp.797-804, DOI: 10.1007/s00216-015-9164-6.

Heaney, L and Suzuki, T (2015) Clinical Mass Spectrometry in Heart Disease, Cardiogenetics, 5(1), pp.5459-5459, DOI: 10.4081/cardiogenetics.2015.5459.

Stevens, D, Cornmell, R, Taylor, D, Grimshaw, SG, Riazanskaia, S, Arnold, DS, Fernstad, SJ, Smith, AM, Heaney, LM, Reynolds, JC, Thomas, CLP, Harker, M (2015) Spatial variations in the microbial community structure and diversity of the human foot is associated with the production of odorous volatiles, FEMS Microbiol Ecol, 91(1), pp.1-11, DOI: 10.1093/femsec/fiu018.



Conferences

Mbasu, RJ, Hakimi, A, Sandhu, JK, Heaney, LM, Quinn, PA, Bhandari, SS, Jones, DJL, Ng, LL (2015) PROTEOMICS OF HUMAN PLASMA IN DIASTOLIC HEART FAILURE (DHF) USING NOVEL CHEMICAL AFFINITY, MIXED MODE MATRIX (M3). In Autumn Meeting of the British-Society-for-Cardiovascular-Research - Translation of Cardiovascular Science to the Clinic, HEART, Univ Glasgow, Glasgow, SCOTLAND, pp.A7-A7, DOI: 10.1136/heartjnl-2015-308734.20.

Khan, NA, Heaney, L, Lindley, MR (2014) Do Elite Games Players Achieve Target VE During Eucapnic Voluntary Hyperpnoea Trails. In , Medicine & Science in Sports & Exercise, pp.526-527, DOI: 10.1249/01.mss.0000495045.34371.7a.

Ferguson, RA, Paley, VR, Ewens, JCW, Heaney, LM, Redden, J (2012) Effect of Neuromuscular Electrostimulation via the Peroneal Nerve on Muscle Soreness Following Intense Intermittent Exercise. In , MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, pp.935-935.



Datasets

Heaney, L, Kang, S, Turner, M, Lindley, M, Thomas, P (2022) Maximal Oxygen Uptake - Exhaled VOC data, DOI: 10.17028/rd.lboro.17074841.

Hatcher, C, Sommer, U, Heaney, L, Millett, J (2021) Supplementary Information files for - Metabolomic analysis reveals reliance on secondary plant metabolites to facilitate carnivory in the Cape sundew, Drosera capensis, DOI: 10.17028/rd.lboro.14188703.

Annese, V, Patil, S, Hu, C, Giagkoulovits, C, Al-Rawhani, M, Grant, J, Macleod, M, Clayton, D, Heaney, L, Daly, R, Accarino, C, Shah, Y, Cheah, B, Beeley, J, Evans, TJ, Jones, R, Barrett, M, Cumming, D (2021) Supplementary information files for A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection, DOI: 10.17028/rd.lboro.14178899.



Other

Bossone, E, Arcopinto, M, Iacoviello, M, Triggiani, V, Cacciatore, F, Maiello, C, Limongelli, G, Masarone, D, Perticone, F, Sciacqua, A, Perrone-Filardi, P, Mancini, A, Volterrani, M, Vriz, O, Castello, R, Passantino, A, Campo, M, Modesti, PA, De Giorgi, A, Monte, I, Puzzo, A, Ballotta, A, Caliendo, L, D'Assante, R, Marra, AM, Salzano, A, Suzuki, T, Cittadini, A, TOSCA Investigators, (2018) Multiple hormonal and metabolic deficiency syndrome in chronic heart failure: rationale, design, and demographic characteristics of the T.O.S.CA. Registry, Recent evidence supports the concept that progression of chronic heart failure (CHF) depends upon an imbalance of catabolic forces over the anabolic drive. In this regard, multiple hormonal deficiency syndrome (MHDS) significantly has impacts upon CHF progression, and is associated with a worse clinical status and increased mortality. The T.O.S.CA. (Trattamento Ormonale nello Scompenso CArdiaco; Hormone Therapy in Heart Failure) Registry (clinicaltrial.gov = NCT02335801) tests the hypothesis that anabolic deficiencies reduce survival in a large population of mild-to-moderate CHF patients. The T.O.S.CA. Registry is a prospective multicenter observational study coordinated by "Federico II" University of Naples, and involves 19 centers situated throughout Italy. Thyroid hormones, insulin-like growth factor-1, total testosterone, dehydroepiandrosteroneand insulin are measured at baseline and every year for a patient-average follow-up of 3 years. Subjects with CHF are divided into two groups: patients with one or no anabolic deficiency, and patients with two or more anabolic deficiencies at baseline. The primary endpoint is the composite of all-cause mortality and cardiovascular hospitalization. Secondary endpoints include the composite of all-cause mortality and hospitalization, the composite of cardiovascular mortality and cardiovascular hospitalization, and change of VO2 peak. Patient enrollment started in April 2013, and was completed in July 2017. Demographics and main clinical characteristics of enrolled patients are provided in this article. Detailed cross-sectional results will be available in late 2018. The T.O.S.CA. Registry represents the most robust prospective observational trial on MHDS in the field of CHF. The study findings will advance our knowledge with regard to the intimate mechanisms of CHF progression and hopefully pave the way for future randomized clinical trials of single or multiple hormonal replacement therapies in CHF. DOI: 10.1007/s11739-018-1844-8.



Getting in touch

Research Office
Loughborough University
Loughborough
Leicestershire
LE11 3TU
researchpolicy@lboro.ac.uk
+44 (0)1509 222453