Loughborough University
Leicestershire, UK
LE11 3TU
+44 (0)1509 263171
Loughborough University

Loughborough University Research Publications

Publications for Elizabeth Akam

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Journal Articles

Nickels, M, Mastana, S, Codd, V, Denniff, M, Akam, E (2022) Comparison of Telomere Length in Young and Master Endurance Runners and Sprinters, Journal of Aging and Physical Activity, 30(3), pp.510-516, ISSN: 1063-8652. DOI: 10.1123/japa.2021-0236.

Nickels, M, Mastana, S, Denniff, M, Codd, V, Akam, E (2022) Pilates and telomere dynamics: A 12-month longitudinal study, Journal of Bodywork and Movement Therapies, 30, pp.118-124, ISSN: 1360-8592. DOI: 10.1016/j.jbmt.2022.02.013.

Mok, J, Brown, M-J, Akam, L, Morris, M (2022) The lasting effects of resistance and endurance exercise interventions on breast cancer patient mental wellbeing and physical fitness, Scientific Reports, 12, 3504, DOI: 10.1038/s41598-022-07446-3.

Brown, M-J, Morris, M, Akam, L (2020) An exploration of the role of exercise in modulating breast cancer progression in vitro: a systematic review and meta-analysis, American Journal of Physiology-Cell Physiology, 320(3), ISSN: 0363-6143. DOI: 10.1152/ajpcell.00461.2020.

Bahsoun, S, Coopman, K, Akam, L (2020) Quantitative assessment of the impact of cryopreservation on human bone marrow-derived mesenchymal stem cells: up to 24 h post-thaw and beyond, Stem Cell Research and Therapy, 11, 540, ISSN: 1757-6512. DOI: 10.1186/s13287-020-02054-2.

Nickels, M, Mastana, S, Denniff, M, Codd, V, Akam, L (2020) Elite swimmers possess shorter telomeres than recreationally active controls, Gene, 769, 145242, ISSN: 0378-1119. DOI: 10.1016/j.gene.2020.145242.

Nickels, M, Mastana, S, Hunter, D, Denniff, M, Codd, V, Akam, L (2020) The effect of a 12-week resistance training intervention on leukocyte telomere length, Heliyon, 6(6), e04151, ISSN: 2405-8440. DOI: 10.1016/j.heliyon.2020.e04151.

Turner, M, Martin, N, Player, DJ, Ferguson, R, Wheeler, P, Green, CJZ, Akam, L, Lewis, M (2020) Characterising hyperinsulinaemia induced insulin resistance in human skeletal muscle cells, Journal of Molecular Endocrinology, 64(3), pp.125-132, ISSN: 0952-5041. DOI: 10.1530/jme-19-0169.

Akam, L, Tansey, S, Hastings, B (2019) The effect of low-resistance high-repetition resistance training on longer-term functional adaptations and total athletic score, Archives of Physical Health and Sports Medicine, 2(2), pp.8-15, ISSN: 2639-1805.

Bahsoun, S, Coopman, K, Akam, L (2019) The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review, Journal of Translational Medicine, 17(1), 397, DOI: 10.1186/s12967-019-02136-7.

Brown, M, Bahsoun, S, Morris, M, Akam, L (2019) Determining conditions for successful culture of multi-cellular 3D tumour spheroids to investigate the effect of mesenchymal stem cells on breast cancer cell invasiveness, Bioengineering, 6(4), 101, ISSN: 2306-5354. DOI: 10.3390/bioengineering6040101.

Kow, M, Akam, L, Singh, P, Singh, M, Cox, N, Bhatti, JS, Tuck, SP, Francis, RM, Datta, H, Mastana, S (2019) Vitamin D receptor (VDR) gene polymorphism and osteoporosis risk in White British men, Annals of Human Biology, 46(5), pp.430-433, ISSN: 0301-4460. DOI: 10.1080/03014460.2019.1659851.

Akam, L and Riley-Smith, K (2019) Pilates conventional or complementary?, Advances in Complementary & Alternative Medicine, 4(4), ACAM.000596.2019, ISSN: 2637-7802. DOI: 10.31031/ACAM.2019.04.000596.

Bahsoun, S, Coopman, K, Forsyth, NR, Akam, L (2019) The role of dissolved oxygen levels on human Mesenchymal Stem Cell culture success, regulatory compliance and therapeutic potential, Stem Cells and Development, ISSN: 1547-3287. DOI: 10.1089/scd.2017.0291.

Butler, SJ, Young, A, Akam, L, Sinha, N, Agrawal, S, Mastana, S (2018) Association of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with coronary artery disease (CAD) in a North Indian population, Cogent Medicine, 5, ISSN: 2331-205X. DOI: 10.1080/2331205X.2018.1478477.

McMullan, C, Dowejko, M, Cox, N, Ghelani, AM, Akam, L, Samanta, A, Mastana, S (2018) Genetic analysis of common variants of MMPs and their involvement in Rheumatoid Arthritis in the East Midlands, UK, Journal of Clinical Genomics, 1(1), pp.1-4.

Turner, M, Player, DJ, Martin, N, Akam, L, Lewis, M (2018) The effect of chronic high insulin exposure upon metabolic and myogenic markers in C2C12 skeletal muscle cells and myotubes, Journal of Cellular Biochemistry, ISSN: 0730-2312. DOI: 10.1002/jcb.26748.

Doody, N, Dowejko, M, Akam, L, Cox, N, Bhatti, JS, Singh, P, Mastana, S (2017) The role of TLR4, TNF-α and IL-1β in type 2 diabetes mellitus development within a North Indian Population, Annals of Human Genetics, 81, pp.141-146, ISSN: 1469-1809. DOI: 10.1111/ahg.12197.

Mastana, S, Prakash, S, Akam, L, Kirby, M, Lindley, M, Sinha, N, Agrawal, S (2017) Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population, Gene, ISSN: 0378-1119. DOI: 10.1016/j.gene.2017.07.050.

Laybourn, S, Akam, L, Cox, N, Singh, P, Mastana, S (2016) Genetic analysis of novel Alu insertion polymorphisms in selected Indian populations, American journal of human biology : the official journal of the Human Biology Council, ISSN: 1042-0533. DOI: 10.1002/ajhb.22881.

Choudhury, S, Akam, L, Mastana, S (2014) Genetic analysis of CYP2D6 polymorphism in Indian populations and its pharmacogenetic implications, Current Pharmacogenomics and Personalized Medicine, 12(2), pp.123-132, ISSN: 1875-6921. DOI: 10.2174/1875692112666140908231649.

Schmidt, JA, Bell, FM, Akam, E, Marshall, C, Dainty, IA, Heinemann, A, Dougall, IG, Bonnert, RV, Sargent, CA (2013) Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2antagonist in clinical development for asthma, British Journal of Pharmacology, 168(7), pp.1626-1638, ISSN: 0007-1188. DOI: 10.1111/bph.12053.

Luker, T, Bonnert, R, Schmidt, J, Sargent, C, Paine, SW, Thom, S, Pairaudeau, G, Patel, A, Mohammed, R, Akam, E, Dougall, I, Davis, AM, Abbott, P, Brough, S, Millichip, I, McInally, T (2011) Switching between agonists and antagonists at CRTh2 in a series of highly potent and selective biaryl phenoxyacetic acids, Bioorganic & Medicinal Chemistry Letters, 21(12), pp.3616-3621, ISSN: 0960-894X. DOI: 10.1016/j.bmcl.2011.04.101.

Akam, E and Strange, PG (2004) Inverse agonist properties of atypical antipsychotic drugs, Biochemical Pharmacology, 67(11), pp.2039-2045, ISSN: 0006-2952. DOI: 10.1016/j.bcp.2004.02.017.

Akam, EC, Challiss, RAJ, Nahorski, SR (2001) G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype, BRITISH JOURNAL OF PHARMACOLOGY, 132(4), pp.950-958, ISSN: 0007-1188. DOI: 10.1038/sj.bjp.0703892.

Akam, EC, Nahorski, SR, Challiss, RAJ (1998) Analysis of M-1, M-2, M-3, M-4-muscarinic cholinoceptor-G protein coupling using [S-35]-GTP gamma S and G alpha-specific immunoprecipitation, BRITISH JOURNAL OF PHARMACOLOGY, 125, ISSN: 0007-1188.

Akam, EC, Challiss, RAJ, Nahorski, SR (1998) Methacholine-stimulated [S-35]-GTP gamma S binding and Ca2+ mobilisation in CHO-cells expressing M-1 and M-3 cholinoceptors, BRITISH JOURNAL OF PHARMACOLOGY, 123, pp.U91-U91, ISSN: 0007-1188.

Akam, EC, Carruthers, AM, Nahorski, SR, Challiss, RAJ (1997) Pharmacological characterization of type 1 alpha metabotropic glutamate receptor-stimulated [S-35]-GTP gamma S binding, BRITISH JOURNAL OF PHARMACOLOGY, 121(6), pp.1203-1209, ISSN: 0007-1188. DOI: 10.1038/sj.bjp.0701238.

Akam, EC, Challiss, RAJ, Nahorski, SR (1996) Inverse agonist activity of atropine at human M(2) and M(4) muscarinic acetylcholine receptors revealed by [S-35]-GTP gamma S binding, BRITISH JOURNAL OF PHARMACOLOGY, 119, pp.P6-P6, ISSN: 0007-1188.

Akam, EC, Carruthers, AM, Nahorski, SR, Challiss, RAJ (1996) Use of [S-35]-GTP gamma S binding to assess type 1 alpha metabotropic glutamate receptor activity in baby hamster kidney cell membranes, BRITISH JOURNAL OF PHARMACOLOGY, 119, pp.P231-P231, ISSN: 0007-1188.


ODonnell, E, Craig, J, Akam, E, Bailey, S (2020) Folic acid supplementation increases cardiac parasympathetic modulation of heart rate in habitually endurance trained and untrained middle-aged men [Abstracts]. In Annual Meeting on Experimental Biology; FASEB JOURNAL, San Diego, CA. DOI: 10.1096/fasebj.2020.34.s1.08662.

Craig, J, Akam, E, Bailey, S, Cox, N, Ferguson, R, O'Donnell, E (2020) Effects of Short-term Folic Acid Supplementation on Brachial Artery Endothelial Function in Habitually Trained and Untrained Postmenopausal Women. In Experimental Biology, FASEB JOURNAL, San Diego, California, US. DOI: 10.1096/fasebj.2020.34.s1.06784.

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LE11 3TU
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