Journal Articles
Po, HF, Houben, AM, Haeb, A-C, Jenkins, DR,
Hill, EJ, Parri, HR, Soriano, J, Saad, D (2024)
Inferring structure of cortical neuronal networks from activity data: A statistical physics approach,
PNAS Nexus, 4(1), pgae565, DOI:
10.1093/pnasnexus/pgae565.
Elsworthy, RJ, Finelli, MJ, Aqattan, S, Dunleavy, C, King, M, Ludlam, A, Tarczyluk, MA, Allen, SL, Prosser, S, Chen, R, Jarquin, SM, Kim, DH, Brown, J, Parri, HR, Aldred, S,
Hill, EJ (2024)
Altered metabolic function induced by Aβ-oligomers and PSEN1 mutations in iPSC-derived astrocytes,
Journal of Neurochemistry, 169(1), ISSN: 0022-3042. DOI:
10.1111/jnc.16267.
Acar, Y, Managh, A,
Hill, EJ, Roach, P (2024)
Tuning Surface Chemistry Impacts on Cardiac Endothelial and Smooth Muscle Cell Development,
Journal of Biomedical Materials Research Part A, 113(1), e37846, ISSN: 1549-3296. DOI:
10.1002/jbm.a.37846.
Hill, E (2024)
Human–machine interfaces and the NEU-CHiP Project: an interview with Dr Eric Hill,
Biochemist, 46(5), pp.4-5, ISSN: 0954-982X. DOI:
10.1042/BIO_2024_926.
Morales Pantoja, IE, Smirnova, L, Muotri, AR, Wahlin, KJ, Kahn, J, Boyd, JL, Gracias, DH, Harris, TD, Cohen-Karni, T, Caffo, BS, Szalay, AS, Han, F, Zack, DJ, Etienne-Cummings, R, Akwaboah, A, Romero, JC, Alam El Din, DM, Plotkin, JD, Paulhamus, BL, Johnson, EC, Gilbert, F, Curley, JL, Cappiello, B, Schwamborn, JC,
Hill, EJ, Roach, P, Tornero, D, Krall, C, Parri, R, Sillé, F, Levchenko, A, Jabbour, RE, Kagan, BJ, Berlinicke, CA, Huang, Q, Maertens, A, Herrmann, K, Tsaioun, K, Dastgheyb, R, Habela, CW, Vogelstein, JT, Hartung, T (2023)
First Organoid Intelligence (OI) workshop to form an OI community,
Frontiers in Artificial Intelligence, 6, 1116870, ISSN: 2624-8212. DOI:
10.3389/frai.2023.1116870.
Elsworthy, RJ,
Hill, EJ, Dunleavy, C, Aldred, S (2022)
The role of ADAM10 in astrocytes: Implications for Alzheimer’s disease,
Frontiers in Aging Neuroscience, 14, 1056507, DOI:
10.3389/fnagi.2022.1056507.
Butcher, JB, Sims, RE, Ngum, NM, Bazzari, AH, Jenkins, SI, King, M,
Hill, EJ, Nagel, DA, Fox, K, Parri, HR, Glazewski, S (2022)
A requirement for astrocyte IP3R2 signaling for whisker experience-dependent depression and homeostatic upregulation in the mouse barrel cortex,
Frontiers in Cellular Neuroscience, 16, 905285, DOI:
10.3389/fncel.2022.905285.
Elsworthy, RJ, Crowe, JA, King, MC, Dunleavy, C, Fisher, E, Ludlam, A, Parri, HR,
Hill, E, Aldred, S (2022)
The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons,
Translational Psychiatry, 12, 285, DOI:
10.1038/s41398-022-02050-5.
Walczak, PA, Perez-Esteban, P, Bassett, DC,
Hill, EJ (2021)
Modelling the central nervous system: tissue engineering of the cellular microenvironment,
Emerging Topics in Life Sciences, 5(4), pp.507-517, ISSN: 2397-8554. DOI:
10.1042/etls20210245.
Hsu, C-C, George, JH, Waller, S, Besnard, C, Nagel, DA,
Hill, E, Coleman, MD, Korsunsky, AM, Cui, Z, Ye, H (2021)
Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds,
Bioactive Materials, 9, pp.358-372, DOI:
10.1016/j.bioactmat.2021.07.008.
Iordachescu, A, Hughes, EAB, Joseph, S,
Hill, E, Grover, LM, Metcalfe, AD (2021)
Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration,
npj Microgravity, 7, 17, DOI:
10.1038/s41526-021-00146-8.
Elsworthy, RJ, King, MC, Grainger, A, Fisher, E, Crowe, JA, Alqattan, S, Ludlam, A,
Hill, E, Aldred, S (2021)
Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiation,
Molecular and Cellular Neuroscience, 114, 103631, ISSN: 1044-7431. DOI:
10.1016/j.mcn.2021.103631.
Holloway, PM, Willaime‐Morawek, S, Siow, R, Barber, M, Owens, RM, Sharma, AD, Rowan, W,
Hill, E, Zagnoni, M (2021)
Advances in microfluidic in vitro systems for neurological disease modeling,
Journal of Neuroscience Research, 99(5), pp.1276-1307, ISSN: 0360-4012. DOI:
10.1002/jnr.24794.
Karikari, TK, Keeling, S,
Hill, E, Lantero Rodrı́guez, J, Nagel, DA, Becker, B, Höglund, K, Zetterberg, H, Blennow, K,
Hill, EJ, Moffat, KG (2020)
Extensive Plasmid Library to Prepare Tau Protein Variants and Study Their Functional Biochemistry,
ACS Chemical Neuroscience, 11(19), pp.3117-3129, ISSN: 1948-7193. DOI:
10.1021/acschemneuro.0c00469.
Crowe, JA, El-Tamer, A, Nagel, D, Koroleva, AV, Madrid-Wolff, J, Olarte, OE, Sokolovsky, S, Estevez-Priego, E, Ludl, A-A, Soriano, J, Loza-Alvarez, P, Chichkov, BN,
Hill, EJ, Parri, HR, Rafailov, EU (2020)
Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks,
Lab on a Chip, 20(10), pp.1792-1806, ISSN: 1473-0197. DOI:
10.1039/c9lc01209e.
Karikari, TK, Nagel, DA, Grainger, A, Clarke-Bland, C, Crowe, J,
Hill, EJ, Moffat, KG (2019)
Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains,
Frontiers in Cellular Neuroscience, 13, DOI:
10.3389/fncel.2019.00296.
Karikari, TK, Nagel, DA, Grainger, A, Clarke-Bland, C,
Hill, EJ, Moffat, KG (2019)
Preparation of stable tau oligomers for cellular and biochemical studies,
Analytical Biochemistry, 566, pp.67-74, ISSN: 0003-2697. DOI:
10.1016/j.ab.2018.10.013.
George, JH, Nagel, D, Waller, S,
Hill, E, Parri, HR, Coleman, MD, Cui, Z, Ye, H (2018)
A closer look at neuron interaction with track-etched microporous membranes,
Scientific Reports, 8(1), 15552, DOI:
10.1038/s41598-018-33710-6.
Grainger, AI, King, MC, Nagel, DA, Parri, HR, Coleman, MD,
Hill, EJ (2018)
In vitro Models for Seizure-Liability Testing Using Induced Pluripotent Stem Cells,
Frontiers in Neuroscience, 12, DOI:
10.3389/fnins.2018.00590.
Arif, M, Kitchen, P, Conner, M,
Hill, E, Nagel, D, Bill, R, Dunmore, S, Armesilla, A, Gross, S, Carmichael, A, Conner, A, Brown, J (2018)
Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA‑MB‑231 breast cancer cell line,
Oncology Letters, ISSN: 1792-1074. DOI:
10.3892/ol.2018.8759.
Rana, KS, Pararasa, C, Afzal, I, Nagel, DA,
Hill, EJ, Bailey, CJ, Griffiths, HR, Kyrou, I, Randeva, HS, Bellary, S, Brown, JE (2017)
Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels,
Cardiovascular Diabetology, 16(1), 147, DOI:
10.1186/s12933-017-0627-2.
Karikari, TK, Turner, A, Stass, R, Lee, LCY, Wilson, B, Nagel, DA,
Hill, EJ, Moffat, KG (2017)
Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag,
Protein Expression and Purification, 130, pp.44-54, ISSN: 1046-5928. DOI:
10.1016/j.pep.2016.09.009.
Monteiro, MC, Coleman, MD,
Hill, EJ, Prediger, RD, Maia, CSF (2017)
Neuroprotection in Neurodegenerative Disease: From Basic Science to Clinical Applications,
Oxidative Medicine and Cellular Longevity, 2017(1), ISSN: 1942-0900. DOI:
10.1155/2017/2949102.
Hill, E, Nagel, D, Parri, R, Coleman, M (2016)
Stem cell‐derived astrocytes: are they physiologically credible?,
The Journal of Physiology, 594(22), pp.6595-6606, ISSN: 0022-3751. DOI:
10.1113/jp270658.
Tarczyluk, MA, Nagel, DA, Parri, HR, Tse, EHY, Brown, JE, Coleman, MD,
Hill, EJ (2015)
Amyloid β 1-42 Induces Hypometabolism in Human Stem Cell-Derived Neuron and Astrocyte Networks,
Journal of Cerebral Blood Flow & Metabolism, 35(8), pp.1348-1357, ISSN: 0271-678X. DOI:
10.1038/jcbfm.2015.58.
Woehrling, EK, Parri, HR, Tse, EHY,
Hill, EJ, Maidment, ID, Fox, GC, Coleman, MD (2015)
A Predictive In Vitro Model of the Impact of Drugs with Anticholinergic Properties on Human Neuronal and Astrocytic Systems,
PLOS ONE, 10(3), pp.e0118786-e0118786, DOI:
10.1371/journal.pone.0118786.
(2015)
Basic and clinical science posters,
Diabetic Medicine, 32(S1), pp.30-100, ISSN: 0742-3071. DOI:
10.1111/dme.12668.
Nagel, DA,
Hill, EJ, O’Neil, J, Mireur, A, Coleman, MD (2014)
The effects of the fungicides fenhexamid and myclobutanil on SH-SY5Y and U-251 MG human cell lines,
Environmental Toxicology and Pharmacology, 38(3), pp.968-976, ISSN: 1382-6689. DOI:
10.1016/j.etap.2014.09.005.
Rana, KS, Arif, M,
Hill, EJ, Aldred, S, Nagel, DA, Nevill, A, Randeva, HS, Bailey, CJ, Bellary, S, Brown, JE (2014)
Plasma irisin levels predict telomere length in healthy adults,
AGE, 36(2), pp.995-1001, ISSN: 0161-9152. DOI:
10.1007/s11357-014-9620-9.
(2014)
Basic and clinical science posters,
Diabetic Medicine, 31(s1), pp.28-73, ISSN: 0742-3071. DOI:
10.1111/dme.12378_1.
Pirttimaki, TM, Codadu, NK, Awni, A, Pratik, P, Nagel, DA,
Hill, EJ, Dineley, KT, Parri, HR (2013)
α7 Nicotinic Receptor-Mediated Astrocytic Gliotransmitter Release: Aβ Effects in a Preclinical Alzheimer’s Mouse Model,
PLoS ONE, 8(11), pp.e81828-e81828, DOI:
10.1371/journal.pone.0081828.
Tarczyluk, MA, Nagel, DA, O’Neil, JD, Parri, HR, Tse, EHY, Coleman, MD,
Hill, EJ (2013)
Functional Astrocyte-Neuron Lactate Shuttle in a Human Stem Cell-Derived Neuronal Network,
Journal of Cerebral Blood Flow & Metabolism, 33(9), pp.1386-1393, ISSN: 0271-678X. DOI:
10.1038/jcbfm.2013.81.
Dias, HKI, Mistry, J, Tarzyluck, M,
Hill, EJ, Bennett, SJ, Polidori, MC, Lip, GYH, Griffiths, HR (2013)
Oxidised LDL-lipids alter redox ratio, lipid raft formation and increase amyloid beta production by SHSY-5Y cells,
Experimental Gerontology, 48(7), pp.688-688, ISSN: 0531-5565. DOI:
10.1016/j.exger.2013.05.022.
Dias, IHK, Chapple, ILC, Milward, M, Grant, MM,
Hill, E, Brown, J, Griffiths, HR (2013)
Sulforaphane Restores Cellular Glutathione Levels and Reduces Chronic Periodontitis Neutrophil Hyperactivity In Vitro,
PLoS ONE, 8(6), pp.e66407-e66407, DOI:
10.1371/journal.pone.0066407.
Hill, EJ, Nagel, DA, O’Neil, JD, Torr, E, Woehrling, EK, Devitt, A, Coleman, MD (2013)
Effects of Lithium and Valproic Acid on Gene Expression and Phenotypic Markers in an NT2 Neurosphere Model of Neural Development,
PLoS ONE, 8(3), pp.e58822-e58822, DOI:
10.1371/journal.pone.0058822.
(2013)
Basic and clinical science posters: adipocyte function,
Diabetic Medicine, 30(s1), pp.30-78, ISSN: 0742-3071. DOI:
10.1111/dme.12091_1.
Woehrling, EK,
Hill, EJ, Nagel, D, Coleman, MD (2013)
Brain-derived neurotrophic factor as an indicator of chemical neurotoxicity: An animal-free CNS cell culture model,
Alternatives to Laboratory Animals, 41(6), pp.503-511, ISSN: 0261-1929. DOI:
10.1177/026119291304100613.
Coleman, MD, O'Neil, JD, Woehrling, EK, Ndunge, OBA,
Hill, EJ, Menache, A, Reiss, CJ (2012)
A Preliminary Investigation into the Impact of a Pesticide Combination on Human Neuronal and Glial Cell Lines In Vitro,
PLoS ONE, 7(8), pp.e42768-e42768, DOI:
10.1371/journal.pone.0042768.
Hill, EJ, Jiménez-González, C, Tarczyluk, M, Nagel, DA, Coleman, MD, Parri, HR (2012)
NT2 Derived Neuronal and Astrocytic Network Signalling,
PLoS ONE, 7(5), pp.e36098-e36098, DOI:
10.1371/journal.pone.0036098.
Woehrling, EK,
Hill, EJ, Torr, EE, Coleman, MD (2011)
Single-Cell ELISA and Flow Cytometry as Methods for Highlighting Potential Neuronal and Astrocytic Toxicant Specificity,
Neurotoxicity Research, 19(3), pp.472-483, ISSN: 1029-8428. DOI:
10.1007/s12640-010-9202-2.
Woehrling, EK,
Hill, EJ, Coleman, MD (2010)
Evaluation of the Importance of Astrocytes When Screening for Acute Toxicity in Neuronal Cell Systems,
Neurotoxicity Research, 17(2), pp.103-113, ISSN: 1029-8428. DOI:
10.1007/s12640-009-9084-3.
Hill, EJ and Vernallis, AB (2008)
Polarized secretion of Leukemia Inhibitory Factor,
BMC Cell Biology, 9(1), 53, DOI:
10.1186/1471-2121-9-53.
Hill, EJ, Woehrling, EK, Prince, M, Coleman, MD (2008)
Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing,
Toxicology, 249(2-3), pp.243-250, ISSN: 0300-483X. DOI:
10.1016/j.tox.2008.05.014.
Woehrling, EK,
Hill, EJ, Coleman, MD (2007)
Development of a neurotoxicity test-system, using human post-mitotic, astrocytic and neuronal cell lines in co-culture,
Toxicology in Vitro, 21(7), pp.1241-1246, ISSN: 0887-2333. DOI:
10.1016/j.tiv.2007.04.011.
