Journal Articles
Frost, O, Ramkilawan, P, Rebbaa, A,
Stolzing, A (2024)
A systematic review of lifespan studies in rodents using stem cell transplantations,
Ageing Research Reviews, 102295, ISSN: 1568-1637. DOI:
10.1016/j.arr.2024.102295.
Admasu, TD, Kim, K, Rae, M, Avelar, R, Gonciarz, RL, Rebbaa, A, de Magalhães, JP, Renslo, AR,
Stolzing, A, Sharma, A (2023)
Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis,
Cell Reports, 42(2), 112058, ISSN: 2211-1247. DOI:
10.1016/j.celrep.2023.112058.
Brauning, A, Rae, M, Zhu, G, Fulton, E, Admasu, TD,
Stolzing, A, Sharma, A (2022)
Aging of the immune system: Focus on natural killer cells phenotype and functions,
Cells, 11(6), 1017, DOI:
10.3390/cells11061017.
Kim, K, Admasu, TD,
Stolzing, A, Sharma, A (2022)
Enhanced co-culture and enrichment of human natural killer cells for the selective clearance of senescent cells,
Aging, 14(5), pp.2131-2147, ISSN: 1945-4589. DOI:
10.18632/aging.203931.
Saravanan, S, Lewis, CJ, Dixit, B, O’Connor, MS,
Stolzing, A, Boominathan, A (2022)
The mitochondrial genome in aging and disease and the future of mitochondrial therapeutics,
Biomedicines, 10(2), 490, DOI:
10.3390/biomedicines10020490.
Olgasi, C, Borsotti, C, Merlin, S, Bergmann, T, Bittorf, P, Adewoye, AB, Wragg, N, Patterson, K, Calabria, A, Benedicenti, F, Cucci, A, Borchiellini, A, Pollio, B, Montini, E, Mazzuca, DM, Zierau, M,
Stolzing, A, Toleikis, PM, Braspenning, J, Follenzi, A (2021)
Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device,
Molecular Therapy - Methods & Clinical Development, 23, pp.551-566, ISSN: 2329-0501. DOI:
10.1016/j.omtm.2021.10.015.
Admasu, TD, Rae, M,
Stolzing, A (2021)
Dissecting primary and secondary senescence to enable new senotherapeutic strategies,
Ageing Research Reviews, 70, pp.101412-101412, ISSN: 1568-1637. DOI:
10.1016/j.arr.2021.101412.
Wragg, NM, Tampakis, D,
Stolzing, A (2020)
Cryopreservation of mesenchymal stem cells using medical grade ice nucleation inducer,
International Journal of Molecular Sciences, 21(22), 8579, ISSN: 1661-6596. DOI:
10.3390/ijms21228579.
Adewoye, AB, Tampakis, D, Follenzi, A,
Stolzing, A (2020)
Multiparameter flow cytometric detection and quantification of senescent cells in vitro,
Biogerontology, 21(6), pp.773-786, ISSN: 1389-5729. DOI:
10.1007/s10522-020-09893-9.
Costa-Marques, L, Johnson, AA,
Stolzing, A (2020)
Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β,
Experimental Cell Research, 395(2), 112203, ISSN: 0014-4827. DOI:
10.1016/j.yexcr.2020.112203.
Kale, A, Sharma, A,
Stolzing, A, Desprez, P-Y, Campisi, J (2020)
Role of immune cells in the removal of deleterious senescent cells,
Immunity and Ageing, 17, 16, ISSN: 1742-4933. DOI:
10.1186/s12979-020-00187-9.
Awan, M, Buriak, I, Fleck, R, Fuller, B, Goltsev, A, Kerby, J, Lowdell, M, Mericka, P, Petrenko, A, Petrenko, Y, Rogulska, O,
Stolzing, A, Stacey, GN (2020)
Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?,
Regen Med, DOI:
10.2217/rme-2019-0145.
Costa-Marques, L, Arnold, K, Pardon, M-C, Leovsky, C, Swarbrick, S, Fabian, C,
Stolzing, A (2019)
Transplantation of bone marrow derived macrophages reduces markers of neuropathology in an APP/PS1 mouse model,
Translational Neurodegeneration, 8(1), 33, DOI:
10.1186/s40035-019-0173-9.
Johnson, AA and
Stolzing, A (2019)
The role of lipid metabolism in aging, lifespan regulation, and age-related disease,
Aging Cell, 18(6), e13048, ISSN: 1474-9718. DOI:
10.1111/acel.13048.
Fleming, J, Capel, A, Rimington, R, Player, DJ,
Stolzing, A, Lewis, M (2019)
Functional regeneration of tissue engineered skeletal muscle in vitro is dependent on the inclusion of basement membrane proteins,
Cytoskeleton, 76(6), pp.371-382, ISSN: 1949-3584. DOI:
10.1002/cm.21553.
Yu-Taeger, L, Stricker-Shaver, J, Arnold, K, Bambynek-Dziuk, P, Novati, A, Singer, E, Lourhmati, A, Fabian, C, Magg, J, Riess, O, Schwab, M,
Stolzing, A, Danielyan, L, Nguyen, HHP (2019)
Intranasal administration of mesenchymal stem cells ameliorates the abnormal dopamine transmission system and inflammatory reaction in the R6/2 mouse model of Huntington disease,
Cells, 8(6), 595, DOI:
10.3390/cells8060595.
Fernández, AF, Bayón, GF, Urdinguio, RG, Toraño, EG, García, MG, Carella, A, Petrus-Reurer, S, Ferrero, C, Martinez-Camblor, P, Cubillo, I, García-Castro, J, Delgado-Calle, J, Pérez-Campo, FM, Riancho, JA, Bueno, C, Menéndez, P, Mentink, A, Mareschi, K, Claire, F, Fagnani, C, Medda, E, Toccaceli, V, Brescianini, S, Moran, S, Esteller, M,
Stolzing, A, de Boer, J, Nisticò, L, Stazi, MA, Fraga, MF (2019)
Corrigendum: H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells,
Genome research, 29(4), DOI:
10.1101/gr.249417.119.
Swarbrick, S, Wragg, N, Ghosh, S,
Stolzing, A (2019)
Systematic review of miRNA as biomarkers in Alzheimer’s disease,
Molecular Neurobiology, 56(9), pp.6156-6167, ISSN: 0893-7648. DOI:
10.1007/s12035-019-1500-y.
Burton, D and
Stolzing, A (2018)
Cellular senescence: immunosurveillance and future immunotherapy,
Ageing Res Rev, DOI:
10.1016/j.arr.2018.02.001.
Swarbrick, S, Efimov, I, Ostanin, VP, Klenerman, D,
Stolzing, A, Ghosh, S (2018)
Anharmonic acoustic effects during DNA hybridization on an electrochemical quartz crystal resonator,
Electrochimica Acta, 269, pp.526-533, ISSN: 0013-4686. DOI:
10.1016/j.electacta.2018.03.014.
Fabian, C, Naaldijk, Y, Leovsky, C, Johnson, AA, Rudolph, L, Jaeger, C, Arnold, K,
Stolzing, A (2017)
Distribution pattern following systemic mesenchymal stem cell injection depends on the age of the recipient and neuronal health,
Stem Cell Research & Therapy, 8(1), DOI:
10.1186/s13287-017-0533-2.
Atesok, K, Fu, FH, Sekiya, I,
Stolzing, A, Ochi, M, Rodeo, SA (2017)
Stem cells in degenerative orthopaedic pathologies: effects of aging on therapeutic potential,
Knee Surgery, Sports Traumatology, Arthroscopy, ISSN: 0942-2056. DOI:
10.1007/s00167-015-3763-9.
Hamidouche, Z, Rother, K, Przybilla, J, Krinner, A, Clay, D, Hopp, L, Fabian, C,
Stolzing, A, Binder, H, Charbord, P, Galle, J (2016)
Bistable epigenetic states explain age-dependent decline in mesenchymal stem cell heterogeneity,
Stem Cells, DOI:
10.1002/stem.2514.
Johnson, A, Naaldijk, Y, Hohaus, C, Meisel, H,
Stolzing, A (2016)
Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors,
Aging, DOI:
10.18632/aging.101035.
Matjusaitis, M, Chin, G, Sarnoski, EA,
Stolzing, A (2016)
Biomarkers to identify and isolate senescent cells,
Ageing research reviews, 29, pp.1-12, ISSN: 1568-1637. DOI:
10.1016/j.arr.2016.05.003.
Naaldijk, Y, Jaeger, C, Fabian, C, Leovsky, C, Blüher, A, Rudolph, L, Hinze, A,
Stolzing, A (2016)
Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice,
Neuropathology and applied neurobiology, 43(4), pp.299-314, ISSN: 0305-1846. DOI:
10.1111/nan.12319.
Stolzing, A and Rohani, LR (2016)
Generation of human induced pluripotent stem cells using non-synthetic mRNA,
Stem Cell Research, 16(3), pp.662-672, ISSN: 1873-5061. DOI:
10.1016/j.scr.2016.03.008.
Heathman, Stolzing, Fabian, C, Rafiq, Coopman, K, Nienow, Kara, B, Hewitt, C (2016)
Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate,
Cytotherapy, 18(4), pp.523-535, ISSN: 1477-2566. DOI:
10.1016/j.jcyt.2016.01.007.
Stolzing, A (2016)
Therapeutic potential of mesenchymal stem cells for pulmonary complications associated with preterm birth,
International Journal of Biochemistry & Cell Biology, 74, pp.18-32, DOI:
10.1016/j.biocel.2016.02.023.
Naaldijk, Y, Johnson, AA, Friedrich-Stockigt, A,
Stolzing, A (2016)
Cryopreservation of dermal fibroblasts and keratinocytes in hydroxyethyl starch–based cryoprotectants,
BMC Biotechnology, ISSN: 1472-6750. DOI:
10.1186/s12896-016-0315-4.
Schmidt, F, Boltze, J, Jager, C, Hofmann, S, Willems, N, Seeger, J, Hartig, W,
Stolzing, A (2015)
Detection and quantification of beta-amyloid, pyroglutamyl A beta, and tau in aged canines,
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 74(9), pp.912-923, ISSN: 0022-3069. DOI:
10.1097/NEN.0000000000000230.
Fernandez, AF, Bayon, GF, Urdinguio, RG, Torano, EG, Garcia, MG, Carella, A, Petrus-Reurer, S, Ferrero, C, Martinez-Camblor, P, Cubillo, I, Garcia-Castro, J, Delgado-Calle, J, Perez-Campo, FM, Riancho, JA, Bueno, C, Menendez, P, Mentink, A, Mareschi, K, Claire, F, Fagnani, C, Medda, E, Toccaceli, V, Brescianini, S, Moran, S, Esteller, M,
Stolzing, A, de Boer, J, Nistico, L, Stazi, MA, Fraga, MF (2015)
H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells,
GENOME RESEARCH, 25(1), pp.27-40, ISSN: 1088-9051. DOI:
10.1101/gr.169011.113.
Heathman, T,
Stolzing, A, Fabian, C, Rafiq, QA, Nienow, AW, Coopman, K, Kara, B, Hewitt, CJ (2015)
Serum-free process development: improving the yield and consistency of human mesenchymal stem cell production,
Cytotherapy, ISSN: 1477-2566. DOI:
10.1016/j.jcyt.2015.08.002.
Naaldijk, Y, Johnson, AA, Ishak, S, Meisel, HJ, Hohaus, C,
Stolzing, A (2015)
Migrational changes of mesenchymal stem cells in response to cytokines, growth factors, hypoxia, and aging,
EXPERIMENTAL CELL RESEARCH, 338(1), pp.97-104, ISSN: 0014-4827. DOI:
10.1016/j.yexcr.2015.08.019.
Leovsky, C, Fabian, C, Naaldijk, Y, Jaeger, C, Jang, HJ, Boehme, J, Rudolph, L,
Stolzing, A (2015)
Biodistribution of in vitro-derived microglia applied intranasally and intravenously to mice: effects of aging,
CYTOTHERAPY, 17(11), pp.1617-1626, ISSN: 1465-3249. DOI:
10.1016/j.jcyt.2015.07.019.
Scutt, N, Johnson, AA, Scutt, A,
Stolzing, A (2015)
Tissue-specific ageing of rat tendon-derived progenitor cells,
Journal of Stem Cell Research & Therapy, 5(10), DOI:
10.4172/2157-7633.1000309.
Stolzing, A (2014) H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells,
Genome Research, Sep 30, pp.1-9.
Rohani, L, Johnson, AA, Arnold, A,
Stolzing, A (2014)
The aging signature: A hallmark of induced pluripotent stem cells?,
Aging Cell, 13(1), pp.2-7, ISSN: 1474-9718. DOI:
10.1111/acel.12182.
Bach, M, Schimmelpfennig, C,
Stolzing, A (2014)
Influence of murine mesenchymal stem cells on proliferation, phenotype, vitality, and cytotoxicity of murine cytokine-induced killer cells in coculture,
PLoS One, 9(2), e88115, DOI:
10.1371/journal.pone.0088115.
Danielyan, L, Beer-Hammer, S,
Stolzing, A, Schafer, R, Siegel, G, Fabian, C, Kahle, P, Biedermann, T, Lourhmati, A, Buadze, M, Novakovic, A, Proksch, B, Gleiter, CH, Frey, WHII, Schwab, M (2014)
Intranasal delivery of bone marrow derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's disease,
Cell Transplantation, X, pp.1-10, ISSN: 0963-6897. DOI:
10.3727/096368914X684970.
Stolzing, A and Haendeler, J (2013)
Aging-mechanisms, models, and translation,
Zeitschrift fur Gerontologie und Geriatrie, 46(7), p.612, ISSN: 0948-6704. DOI:
10.1007/s00391-013-0528-2.
Hodzic, M, Naaldijk, Y,
Stolzing, A (2013)
Regulating aging in adult stem cells with microRNA,
Zeitschrift fur Gerontologie und Geriatrie, 46(7), pp.629-634, ISSN: 0948-6704. DOI:
10.1007/s00391-013-0531-7.
Naaldijk, Y, Friedrich-Stöckigt, A, Sethe, S, Stolzing, A (Accepted for publication) Comparison of different cooling rates for fibroblast and keratinocyte cryopreservation, Journal of Tissue Engineering and Regenerative Medicine, ISSN: 1932-6254. DOI: 10.1002/term.1815.
Naaldijk, Y, Federova, V,
Stolzing, A (2013)
Cryopreservation of human umbilical cord-derived mesenchymal stem cells in complex sugar based cryoprotective solutions,
Journal of Biotechnology Letters, 4(2), pp.95-102, ISSN: 0976-7045.
Fuellen, G, Dengjel, J, Hoeflich, A, Hoeijemakers, J, Kestler, HA, Kowald, A, Priebe, S, Rebholz-Schuhmann, D, Schmeck, B, Schmitz, U,
Stolzing, A, Sühnel, J, Wuttke, D, Vera, J (2012)
Systems biology and bioinformatics in aging research: A workshop report,
Rejuvenation Research, 15(6), pp.631-641, ISSN: 1549-1684. DOI:
10.1089/rej.2012.1360.
Johnson, AA, Akman, K, Calimport, SRG, Wuttke, D,
Stolzing, A, De Magalhães, JP (2012)
The role of DNA methylation in aging, rejuvenation, and age-related disease,
Rejuvenation Research, 15(5), pp.483-494, ISSN: 1549-1684. DOI:
10.1089/rej.2012.1324.
Stolzing, A, Bauer, E, Scutt, A (2012)
Suspension cultures of bone-marrow-derived mesenchymal stem cells: Effects of donor age and glucose level,
Stem Cells and Development, 21(14), pp.2718-2723, ISSN: 1547-3287. DOI:
10.1089/scd.2011.0406.
Naaldijk, Y, Staude, M, Fedorova, V,
Stolzing, A (2012)
Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide,
BMC Biotechnology, 12, DOI:
10.1186/1472-6750-12-49.
Hinze, A and
Stolzing, A (2012)
Microglia differentiation using a culture system for the expansion of mice non-adherent bone marrow stem cells,
Journal of Inflammation (United Kingdom), 9.
Stolzing, A, Naaldijk, Y, Fedorova, V, Sethe, S (2012)
Hydroxyethylstarch in cryopreservation - Mechanisms, benefits and problems,
Transfusion and Apheresis Science, 46(2), pp.137-147, ISSN: 1473-0502. DOI:
10.1016/j.transci.2012.01.007.
Colley, H, McArthur, SL,
Stolzing, A, Scutt, A (2012)
Culture on fibrin matrices maintains the colony-forming capacity and osteoblastic differentiation of mesenchymal stem cells,
Biomedical Materials (Bristol), 7(4), ISSN: 1748-6041. DOI:
10.1088/1748-6041/7/4/045015.
Hinze, A and
Stolzing, A (2012)
Microglia differentiation using a culture system for the expansion of mice non-adherent bone marrow stem cells,
Journal of Inflammation (United Kingdom), 9, DOI:
10.1186/1476-9255-9-12.
Paulsen, K, Tauber, S, Timm, J, Goelz, N, Dumrese, C,
Stolzing, A, Hass, R, Ullrich, O (2011)
The cannabinoid receptors agonist WIN55212-2 inhibits macrophageal differentiation and alters expression and phosphorylation of cell cycle control proteins,
Cell Communication and Signaling, 9, DOI:
10.1186/1478-811X-9-33.
Stolzing, A, Colley, H, Scutt, A (2011)
Effect of age and diabetes on the response of mesenchymal progenitor cells to fibrin matrices,
International Journal of Biomaterials, ISSN: 1687-8787. DOI:
10.1155/2011/378034.
Hinze, A and
Stolzing, A (2011)
Differentiation of mouse bone marrow derived stem cells toward microglia-like cells,
BMC Cell Biology, 12, DOI:
10.1186/1471-2121-12-35.
Stolzing, A and Glaser, V (2011)
Personal profile: Interview with Alexandra Stolzing, Ph.D,
Rejuvenation Research, 14(3), pp.347-348, ISSN: 1549-1684. DOI:
10.1089/rej.2011.1219.
Efimenko, A, Starostina, E, Kalinina, N,
Stolzing, A (2011)
Angiogenic properties of aged adipose derived mesenchymal stem cells after hypoxic conditioning,
Journal of Translational Medicine, 9, DOI:
10.1186/1479-5876-9-10.
Stolzing, A, Sellers, D, Llewelyn, O, Scutt, A (2010)
Diabetes induced changes in rat mesenchymal stem cells,
Cells Tissues Organs, 191(6), pp.453-465, ISSN: 1422-6405. DOI:
10.1159/000281826.
Fricke, S, Ackermann, M,
Stolzing, A, Schimmelpfennig, C, Hilger, N, Jahns, J, Hildebrandt, G, Emmrich, F, Ruschpler, P, Pösel, C, Kamprad, M, Sack, U (2009)
Allogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment,
PLoS ONE, 4(7), DOI:
10.1371/journal.pone.0006157.
Stolzing, A, Jones, E, McGonagle, D, Scutt, A (2008)
Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies,
Mechanisms of Ageing and Development, 129(3), pp.163-173, ISSN: 0047-6374. DOI:
10.1016/j.mad.2007.12.002.
Stolzing, A, Hescheler, J, Sethe, S (2007)
Fusion and regenerative therapies: Is immortality really recessive?,
Rejuvenation Research, 10(4), pp.571-586, ISSN: 1549-1684. DOI:
10.1089/rej.2007.0570.
Schloendorn, J, Sethe, S,
Stolzing, A (2007)
Cellular therapy using microglial cells,
Rejuvenation Research, 10(1), pp.87-99, ISSN: 1549-1684. DOI:
10.1089/rej.2006.0511.
Poppek, D, Keck, S, Ermak, G, Jung, T,
Stolzing, A, Ullrich, O, Davies, KJA, Grune, T (2006)
Phosphorylation inhibits turnover of the tau protein by the proteasome: Influence of RCAN1 and oxidative stress,
Biochemical Journal, 400(3), pp.511-520, ISSN: 0264-6021. DOI:
10.1042/BJ20060463.
Stolzing, A, Sethe, S, Scutt, AM (2006)
Stressed stem cells: Temperature response in aged mesenchymal stem cells,
Stem Cells and Development, 15(4), pp.478-487, ISSN: 1547-3287. DOI:
10.1089/scd.2006.15.478.
Stolzing, A and Scutt, A (2006)
Effect of reduced culture temperature on antioxidant defences of mesenchymal stem cells,
Free Radical Biology and Medicine, 41(2), pp.326-338, ISSN: 0891-5849. DOI:
10.1016/j.freeradbiomed.2006.04.018.
Stolzing, A, Widmer, R, Jung, T, Voss, P, Grune, T (2006)
Tocopherol-mediated modulation of age-related changes in microglial cells: Turnover of extracellular oxidized protein material,
Free Radical Biology and Medicine, 40(12), pp.2126-2135, ISSN: 0891-5849. DOI:
10.1016/j.freeradbiomed.2006.02.011.
Stolzing, A and Scutt, A (2006)
Age-related impairment of mesenchymal progenitor cell function,
Aging Cell, 5(3), pp.213-224, ISSN: 1474-9718. DOI:
10.1111/j.1474-9726.2006.00213.x.
Stolzing, A, Widmer, R, Jung, T, Voss, P, Grune, T (2006)
Degradation of glycated bovine serum albumin in microglial cells,
Free Radical Biology and Medicine, 40(6), pp.1017-1027, ISSN: 0891-5849. DOI:
10.1016/j.freeradbiomed.2005.10.061.
Stolzing, A, Coleman, N, Scutt, A (2006)
Glucose-induced replicative senescence in mesenchymal stem cells,
Rejuvenation Research, 9(1), pp.31-35, ISSN: 1549-1684. DOI:
10.1089/rej.2006.9.31.
Sethe, S, Scutt, A,
Stolzing, A (2006)
Aging of mesenchymal stem cells,
Ageing Research Reviews, 5(1), pp.91-116, ISSN: 1568-1637. DOI:
10.1016/j.arr.2005.10.001.
Mishto, M, Bellavista, E, Santoro, A,
Stolzing, A, Ligorio, C, Nacmias, B, Spazzafumo, L, Chiappelli, M, Licastro, F, Sorbi, S, Pession, A, Ohm, T, Grune, T, Franceschi, C (2006)
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains,
Neurobiology of Aging, 27(1), pp.54-66, ISSN: 0197-4580. DOI:
10.1016/j.neurobiolaging.2004.12.004.
Stolzing, A, Sethe, S, Grune, T (2005)
Chronically active: Activation of microglial proteolysis in ageing and neurodegeneration,
Redox Report, 10(4), pp.207-213, ISSN: 1351-0002. DOI:
10.1179/135100005X70198.
Sudre, L, Cheung, F, Kevorkian, L, Young, DA, Darrah, C, Donell, ST, Shepstone, L, Porter, S, Brockbank, S, Edwards, DR, Parker, AE, Clark, IM, Boubriak, OA, Urban, JPG, Cui, Z, Tew, SR, Li, Y, Tweats, LM, Hawkins, RE, Hardingham, TE, Green, D, Partridge, KA, Leveque, I, Mann, S, Oreffo, ROC, Ball, SG, Kielty, CM, Qin, M, Tai, G, Polak, JM, Bishop, AE,
Stolzing, A, Scutt, A, Screen, HRC, Shelton, JC, Bader, DL, Lee, DA, Hall, A, Hayes, A, Brown, L, Tubo, R, Caterson, B, Blain, EJ, Gilbert, SJ, Duance, VC, Davies, L, Duance, V, Shengda, Z, Wu, MH, Xu, X, Heywood, HK, Sims, T, Miot, S, Martin, I, Roughley, PJ, Soranzo, C, Pavesio, A, Hollander, AP, Yang, X, Webb, D, Blaker, J, Maquet, V, Boccaccini, AR, Cooper, C, Eves, P, Beck, AJ, Shard, AG, Gawkrodger, DJ, Mac Neil, S, Rajpar, MH, Kadler, KE, Thornton, DJ, Briggs, MD, Boot-Handford, RP, Ellis, MJ, Tai, CC, Perera, S, Chaudhuri, JB, Callender, P, Mason, DJ, Colley, H, Mc Arthur, S, Mirmalek-Sani, SH, Roach, HI, Hanley, NA, Wilson, DI, MacIntosh, AC, Crawford, A, Hatton, PV, Wallis, G, Shah, R, Knowles, JC, Hunt, NP, Lewis, MP, Rippon, HJ, Ali, BE, De Bank, PA, Kellam, B, Shakesheff, KM (2005)
British society for matrix biology autumn meeting,
International Journal of Experimental Pathology, 86(3), ISSN: 0959-9673. DOI:
10.1111/j.0959-9673.2005.00426.x.
Stolzing, A and Grune, T (2004)
Free radicals: Oxidative stress makes the skin look old,
Pharmazeutische Zeitung, 149(26), pp.16-21, ISSN: 0031-7136.
Ernst, A,
Stolzing, A, Sandig, G, Grune, T (2004)
Protein oxidation and the degradation of oxidized proteins in the rat oligodendrocyte cell line OLN 93-antioxidative effect of the intracellular spin trapping agent PBN,
Molecular Brain Research, 122(2), pp.126-132, ISSN: 0169-328X. DOI:
10.1016/j.molbrainres.2003.12.005.
Stolzing, A and Grune, T (2004)
Neuronal apoptotic bodies: phagocytosis and degradation by primary microglial cells,
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 18(6), pp.743-745, DOI:
10.1096/fj.03-0374fje.
Stolzing, A and Sethe, S (2004)
Watch your notch: A link between aging and stem cell fate?,
Rejuvenation Research, 7(1), pp.9-11, ISSN: 1549-1684. DOI:
10.1089/154916804323105035.
Ernst, A,
Stolzing, A, Sandig, G, Grune, T (2004)
Antioxidants effectively prevent oxidation-induced protein damage in OLN 93 cells,
Archives of Biochemistry and Biophysics, 421(1), pp.54-60, ISSN: 0003-9861. DOI:
10.1016/j.abb.2003.10.008.
Stolzing, A and Grune, T (2003)
Impairment of protein homeostasis and decline of proteasome activity in microglial cells from adult wistar rats,
Journal of Neuroscience Research, 71(2), pp.264-271, ISSN: 0360-4012. DOI:
10.1002/jnr.10478.
Selman, C, Grune, T,
Stolzing, A, Jakstadt, M, McLaren, JS, Speakman, JR (2002)
The consequences of acute cold exposure on protein oxidation and proteasome activity in short-tailed field voles, Microtus agrestis,
Free Radical Biology and Medicine, 33(2), pp.259-265, ISSN: 0891-5849. DOI:
10.1016/S0891-5849(02)00874-2.
Stolzing, A, Wengner, A, Grune, T (2002)
Degradation of oxidized extracellular proteins by microglia,
Archives of Biochemistry and Biophysics, 400(2), pp.171-179, ISSN: 0003-9861. DOI:
10.1016/S0003-9861(02)00003-6.
Stolzing, A and Grune, T (2001)
The proteasome and its function in the aging process,
H+G Zeitschrift fur Hautkrankheiten, 76(10), pp.604-609, ISSN: 0301-0481.
Stolzing, A and Grune, T (2001)
The proteasome and its function in the ageing process,
Clinical and Experimental Dermatology, 26(7), pp.566-572, ISSN: 0307-6938. DOI:
10.1046/j.1365-2230.2001.00867.x.
Merker, K,
Stolzing, A, Grune, T (2001)
Proteolysis, caloric restriction and aging,
Mechanisms of Ageing and Development, 122(7), pp.595-615, ISSN: 0047-6374. DOI:
10.1016/S0047-6374(01)00219-6.
Conferences
Cucci, A, Olgasi, C, Merlin, S, Borsotti, C, Bergmann, T, Bittorf, P, Patterson, K, Mazzuca, DM, Stolzing, A, Zierau, M, Toleikis, PM, Benedicenti, F, Calabria, A, Montini, E, Braspenning, J, Follenzi, A (Accepted for publication) Combined gene and cell therapy for the treatment of Hemophilia A within an implantable therapeutic device [Abstract]. In 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, ELECTR NETWORK, pp.583-584.
Olgasi, C, Bergmann, T, Merlin, S, Borsotti, C, Patterson, KG, Mazzuca, DM, Adewoye, AB,
Stolzing, A, Zierau, M, Toleikis, PM, Braspenning, J, Follenzi, A (2019)
Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A. In
ESGCT 27th Annual Congress in collaboration with SETGyc Meeting, Barcelona, SPAIN.
Olgasi, C, Merlin, S, Borsotti, C, Bergmann, T, Mazzucca, DM,
Stolzing, A, Zierau, M, Toleikis, PM, Braspenning, J, Follenzi, A (2019)
Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A. In
HUMAN GENE THERAPY, Italy, pp.A61-A61.
Olgasi, C, Merlin, S, Borsotti, C, Bergmann, T, Mazzucca, DM,
Stolzing, A, Zierau, M, Toleikis, PM, Braspenning, J, Follenzi, A (2018)
Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A. In
Changing the Face of Modern Medicine: Stem Cell and Gene Therapy, HUMAN GENE THERAPY, Lausanne, pp.A61-A61.
Olgasi, C, Merlin, S, Bittorf, P, Mazzuca, D,
Stolzing, A, Toleikidis, P, Zierau, M, Follenzi, A, Braspenning, J, Bergmann, T (2018)
HemAcure: Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A. In
WFH 2018 World Congress, HAEMOPHILIA, Glasgow, UK, pp.66-66.
Yu-Taeger, L, Stricker-Shaver, J, Arnold, K, Bambynek-Dziuk, P, Novati, A, Singer, E, Claire, F, Magg, J, Riess, O,
Stolzing, A, Danielyan, L, Nguyen, HP (2018)
INTRANASAL ADMINISTRATION OF MESENCHYMAL STEM CELLS AMELIORATES THE ABNORMAL DOPAMINE TRANSMISSION SYSTEM AND INFLAMMATORY REACTION IN THE R6/2 MOUSE MODEL OF HUNTINGTON DISEASE. In
EHDN 2018 Plenary Meeting, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vienna, Austria, pp.A96-A96, DOI:
10.1136/jnnp-2018-EHDN.258.
Olgasi, C, Merlin, S, Bergmann, T, Borsotti, C, Mazzuca, DM,
Stolzing, A, Zierau, M, Toleikis, P, Braspenning, J, Follenzi, A (2017)
Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A. In
ESGCT XXV Anniversary Congress in Collaboration with the German Society for Gene Therapy October 17–20, 2017 Berlin, Germany, HUMAN GENE THERAPY, Berlin, Germany, pp.A92-A92.
Arnold, K, Fabian, C,
Stolzing, A (2017)
Microglia based Alzheimer therapy. In
Oxygen Club, Free Radical Biology and Medicine, Germany, Berlin, pp.S72-S72, DOI:
10.1016/j.freeradbiomed.2017.04.245.
Wragg, N and
Stolzing, A (2017)
Investigating ice nucleation temperature effects on mesenchymal stem cell recovery from cryostorage [Abstract]. In
Advancing Tissue and Regenerative Engineering in UK Medicine (ATREUM), Crewe Hall, Weston Road, Crewe, CW1 6UZ, pp.60-60, ISBN: 9780995594104.
Stolzing, A (2016)
Cryopreservation of Mesenchymal Stem Cells- Can and should we avoid DMSO? [Powerpoint Presentation]. In
3rd IABS Conference on Cell Therapy, Manufacturing and Testing, London.
Fabian, C, Naaldijk, Y,
Stolzing, A (2015)
Alzheimer: nasal transplantation of microglia. In
, Bregenz, AUSTRIA, pp.93-93, DOI:
10.1016/j.exger.2015.01.010.
Walles, H, Kaufmann, M, Traube, A, Pretsch, F, Bernhardt, F,
Stolzing, A (2011)
Skin from the factory - Automated Tissue Engineering on Demand. In
, JOURNAL OF INVESTIGATIVE DERMATOLOGY, pp.S49-S49.
Hinze, A and
Stolzing, A (2010)
Transplantation of bone marrow derived stem cells into Alzheimer mice. In
, ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE, pp.136-137.
Stolzing, A, Ishak, S, Lay, J (2010)
Hypoxia and inflammation as regulators of MSC migration. In
, INFLAMMATION RESEARCH, pp.S156-S157.
Sack, U, Ackermann, M,
Stolzing, A, Hilger, N, Schimmelpfennig, C, Jahns, J, Hildebrandt, G, Emmrich, F, Boltze, J, Kamprad, M, Fricke, S (2009)
ALLOGENEIC NON-ADHERENT BONE MARROW CELLS DO NOT LEAD TO ALLOGENEIC ENGRAFTMENT BUT FACILITATE HEMATOPOIETIC RECOVERY. In
, CYTOMETRY PART B-CLINICAL CYTOMETRY, pp.431-431.
Hinze, A and
Stolzing, A (2009)
In vitro differentiation of bone marrow stem cells toward microglia and functional testing in brain slices and in vivo. In
, JOURNAL OF NEUROCHEMISTRY, pp.79-79.
Hinze, A and
Stolzing, A (2009)
Differentiation of Adult Stem Cells towards Microglial Cells. In
, TISSUE ENGINEERING PART A, pp.720-721.
Stolzing, A, Jones, E, McGonagal, D, Scutt, A (2006)
Mesenchymal stem cells: Coming of age?. In
, CYTOTHERAPY, pp.39-40.
Mishto, M, Bellavista, E, Santoro, A,
Stolzing, A, Ligorio, C, Bertoni-Freddari, C, Pession, A, Ohm, T, Grune, T, Franceschi, C (2006)
Immunoproteasome in the brain: studies in Alzheimer's disease and on young and old humans and primates. In
, FREE RADICAL RESEARCH, pp.S61-S61.
Stolzing, A and Scutt, A (2005)
Do adult stem cells age?. In
, INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, pp.A8-A8.
Stolzing, A and Grune, T (2003)
Protein aggregates and the development of neurodegenerative diseases. In
, FREE RADICALS, NITRIC OXIDE, AND INFLAMMATION: MOLECULAR, BIOCHEMICAL, AND CLINICAL ASPECTS, pp.170-181, ISBN: 1-58603-243-7.
Stolzing, A and Grune, T (2003)
The fate of neuronal apoptotic material-pragocytosis and degradation by microglia-. In
, FREE RADICAL RESEARCH, pp.29-29.
