Journal Articles
Luo, J, Su, Q, Yu, Q, Zhai, X, Zou, Y, Yang, H (Accepted for publication) Application of efficient and sustainable freeze-dissolving technology in manufacturing of KHCO3 ultrafine particles, Green Chemical Engineering, 5(2), pp.266-272, ISSN: 2666-9528. DOI: 10.1016/j.gce.2023.07.003.
Yan, Y, Vladisavljević, GT, Lin, Z,
Yang, H, Zhang, X, Yuan, W (2024)
PEGDA hydrogel microspheres with encapsulated salt for versatile control of protein crystallization,
Journal of Colloid and Interface Science, 660, pp.574-584, ISSN: 0021-9797. DOI:
10.1016/j.jcis.2024.01.125.
Liang, X, Liu, S, Li, Z, Deng, Y, Jiang, Y,
Yang, H (2024)
Efficient cocrystal coformer screening based on a Machine learning Strategy: A case study for the preparation of imatinib cocrystal with enhanced physicochemical properties,
European Journal of Pharmaceutics and Biopharmaceutics, 196, pp.114201-114201, ISSN: 0939-6411. DOI:
10.1016/j.ejpb.2024.114201.
Liu, S, Liu, W, Deng, Y, Li, Z, Li, M, Sun, C, Jiang, Y,
Yang, H (2024)
Modification of solid form of drug in oil-in-water emulsion: Effect of self-assembly of the emulsifier glycyrrhizic acid,
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 681, ISSN: 0927-7757. DOI:
10.1016/j.colsurfa.2023.132808.
Shao, Y, Han, R, Tao, T, Wei, J, Han, D,
Yang, H, Gong, J (2023)
Practical techniques for protein crystallization: additive assistance and external field intensification,
CrystEngComm, DOI:
10.1039/d3ce00995e.
Li, B, Yao, T, Tao, T, Han, D,
Yang, H, Gao, Z, Gong, J (2023)
Enhancement and Regulation of Peptide Crystallization with the Application of Taylor Vortex: A Case Study of Vancomycin,
Industrial & Engineering Chemistry Research, 62(50), pp.21760-21769, ISSN: 0888-5885. DOI:
10.1021/acs.iecr.3c02833.
Tian, W, Li, W,
Yang, H (2023)
Protein Nucleation and Crystallization Process with Process Analytical Technologies in a Batch Crystallizer,
Crystal Growth & Design, 23(7), pp.5181-5193, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.3c00411.
Yu, Q, Li, J, Liu, C,
Yang, H (2023)
Solubility correlation by model with partial molar volume,
Canadian Journal of Chemical Engineering, 101(7), pp.4151-4159, ISSN: 0008-4034. DOI:
10.1002/cjce.24709.
Zheng, Z, Deng, Y, Xie, W, Chen, S, Liang, X, Liu, S, Jiang, Y,
Yang, H (2023)
Co-Former Screening Method for Multicomponent Crystals Based on Partial Least Squares Regression: A Case Study of Ciprofloxacin,
Crystal Growth & Design, 23(5), pp.3244-3257, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.2c01414.
Deng, Y, Luo, W, Zheng, Z, Wei, G, Liu, S, Jiang, Y,
Yang, H (2023)
Prediction of co-amorphous formation using non-bonded interaction energy: Molecular dynamic simulation and experimental validation,
Chemical Engineering Science, 272, pp.118618-118618, ISSN: 0009-2509. DOI:
10.1016/j.ces.2023.118618.
Liu, W, Li, Z, Wang, Z, Huang, Z, Sun, C, Liu, S, Jiang, Y,
Yang, H (2023)
Functional System Based on Glycyrrhizic Acid Supramolecular Hydrogel: Toward Polymorph Control, Stabilization, and Controlled Release,
ACS Applied Materials & Interfaces, 15(6), pp.7767-7776, ISSN: 1944-8244. DOI:
10.1021/acsami.2c19903.
Tian, W, Ogunyinka, O, Oretti, C, Bandulasena, HCH, Rielly, C,
Yang, H (2023)
Protein crystallisation with gas microbubbles as soft template in a microfluidic device,
Molecular Systems Design & Engineering, 8(10), pp.1275-1285, DOI:
10.1039/d3me00058c.
Luo, J, Su, Q, Yu, Q, Zhai, X, Zou, Y,
Yang, H (2023)
Fast and simple preparation of microparticles of KHCO3 by a freeze-dissolving method with single solvent or additional antisolvent,
RSC Sustainability, 1(8), pp.1982-1988, DOI:
10.1039/d3su00234a.
Lin, Z, Tian, W, Su, Y, Yadav, VK,
Yang, H (2022)
Positive and negative effects of graphite flake and monolayer graphene oxide templates on protein crystallization,
Particuology, 79, pp.27-34, ISSN: 1674-2001. DOI:
10.1016/j.partic.2022.10.014.
Li, L, Zhu, X,
Yang, H, Liang, B, Yuan, L, Hu, Y, Chen, F, Han, X (2022)
Phase-Field Model for Drug Release of Water-Swellable Filaments for Fused Filament Fabrication,
Molecular Pharmaceutics, 19(8), pp.2854-2867, ISSN: 1543-8384. DOI:
10.1021/acs.molpharmaceut.2c00217.
Ma, Y, Niu, Y,
Yang, H, Dai, J, Lin, J, Wang, H, Wu, S, Yin, Q, Zhou, L, Gong, J (2022)
Prediction and design of cyclodextrin inclusion complexes formation via machine learning-based strategies,
Chemical Engineering Science, 261, 117946, ISSN: 0009-2509. DOI:
10.1016/j.ces.2022.117946.
Yu, Q, Wang, Y, Luo, J,
Yang, H (2022)
Freeze-dissolving method: a fast green technology for producing nanoparticles and ultrafine powder,
ACS Sustainable Chemistry & Engineering, 10(24), pp.7825-7832, ISSN: 2168-0485. DOI:
10.1021/acssuschemeng.2c02270.
Deng, Y, Chen, Y, Xie, F, Tang, J, Zhang, R,
Yang, H, Jiang, Y, Liu, S (2022)
Minoxidil Multi-Component Crystals with Aromatic Carboxylic Acids: Theoretical Calculation and Structural Analysis,
Crystal Growth and Design, 22(6), pp.3941-3953, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.2c00339.
Sun, M,
Yang, H, Miao, X, Wang, W, Wang, J (2022)
Macromolecular protein crystallisation with biotemplate of live cells,
Scientific Reports, 12(1), 3005, DOI:
10.1038/s41598-022-06999-7.
Tao, T, Gao, Z, Fang, C, Zhang, J, Xu, J,
Yang, H, Gong, J (2022)
Enhancement of protein crystallization with the application of Taylor vortex and Poly(ionic liquid)s,
Chemical Engineering Science, 252, 117501, ISSN: 0009-2509. DOI:
10.1016/j.ces.2022.117501.
Xue, Y, Yan, Y, Si, Z, Zhang, Q,
Yang, H, Zhang, X, Zhou, X (2022)
Prediction of metastable zone widths of ammonium sulphate: modification of the nucleation potential model in an electrolyte system,
CrystEngComm, 24(48), pp.8457-8466, DOI:
10.1039/d2ce01018f.
Wang, L,
Yang, H, Sun, Z, Bao, Y, Yin, Q (2021)
Wet milling, seeding, and ultrasound in the optimization of the oiling-out crystallization process,
Industrial & Engineering Chemistry Research, 60(50), pp.18452-18463, ISSN: 0888-5885. DOI:
10.1021/acs.iecr.1c04167.
Tian, W, Rielly, C,
Yang, H (2021)
Protein crystallisation with air bubble templates: Case of gas-liquid-solid interfaces,
CrystEngComm, 23(46), pp.8159-8168, DOI:
10.1039/d1ce01034d.
Choi, H, Wei, Z, You, JB,
Yang, H, Zhang, X (2021)
Effects of chemical and geometric microstructures on the crystallization of surface droplets during solvent exchange,
Langmuir, 37(17), pp.5290-5298, ISSN: 0743-7463. DOI:
10.1021/acs.langmuir.1c00354.
Zhang, K, Li, X, Wang, Z, Li, G, Ma, B, Chen, H, Li, N,
Yang, H, Wang, Y, Liu, B (2021)
Systemic Expression, Purification, and Initial Structural Characterization of Bacteriophage T4 Proteins Without Known Structure Homologs,
Frontiers in Microbiology, 12, ISSN: 1664-302X. DOI:
10.3389/fmicb.2021.674415.
Wang, L, Bao, Y, Sun, Z, Pinfield, V, Yin, Q,
Yang, H (2021)
Investigation of agglomeration in the presence of oiling out in the antisolvent crystallization process,
Industrial & Engineering Chemistry Research, 60(10), pp.4110-4119, ISSN: 0888-5885. DOI:
10.1021/acs.iecr.1c00491.
Shi, P, Xu, S,
Yang, H, Wu, S, Tang, W, Wang, J, Gong, J (2021)
Use of additives to regulate solute aggregation and direct conformational polymorph nucleation of pimelic acid,
IUCrJ, 8(Part 2), pp.161-167, DOI:
10.1107/s2052252521000063.
Chen, W, Cheng, TNH, Khaw, LF, Li, X,
Yang, H, Ouyang, J, Heng, JYY (2021)
Protein purification with nanoparticle-enhanced crystallisation,
Separation and Purification Technology, 255, ISSN: 1383-5866. DOI:
10.1016/j.seppur.2020.117384.
Si, Z, Li, A, Yan, YZ, Zhang, X,
Yang, H (2021)
Interaction of Metastable Zone Width and Induction Time Based on Nucleation Potential,
Industrial and Engineering Chemistry Research, ISSN: 0888-5885. DOI:
10.1021/acs.iecr.0c04742.
Yu, Q, Jia, W, Pu, J, Wang, Y,
Yang, H (2020)
Cocrystallization of urea and succinic acid in “Nano-Crystallizer”,
Chemical Engineering Science, 229, pp.116082-116082, ISSN: 0009-2509. DOI:
10.1016/j.ces.2020.116082.
Li, X, Chen, W,
Yang, H, Yang, Z, Heng, JYY (2020)
Protein crystal occurrence domains in selective protein crystallisation for bio-separation,
CrystEngComm, 22(27), pp.4566-4572, DOI:
10.1039/d0ce00642d.
Wang, L,
Yang, H, Si, Z, Yan, Y, Zhang, X, Zhou, X (2020)
Solubility and thermodynamics of D-glucosamine 2-sulfate sodium salt in water and binary solvent mixtures with methanol, ethanol and n-propanol,
Journal of Molecular Liquids, 300, ISSN: 0167-7322. DOI:
10.1016/j.molliq.2019.112218.
Chen, W, Park, SJ, Kong, F, Li, X,
Yang, H, Heng, JYY (2020)
High Protein-Loading Silica Template for Heterogeneous Protein Crystallization,
Crystal Growth & Design, 20(2), pp.866-873, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.9b01252.
Zhu, Y,
Yang, H, Si, Z, Zhang, X (2020)
Solubility and thermodynamics of L-hydroxyproline in water and (methanol, ethanol, n-propanol) binary solvent mixtures,
Journal of Molecular Liquids, 298, ISSN: 0167-7322. DOI:
10.1016/j.molliq.2019.112043.
Song, Y, Wu, Y, Jiang, Y,
Yang, H, Jiang, Y (2020)
Polymers and Solvent-Induced Polymorphic Selection and Preferential Orientation of Pyrazinamide Crystal,
Crystal Growth & Design, 20(1), pp.352-361, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.9b01287.
Zhang, X, Wei, Z, Choi, H, Hao, H,
Yang, H (2020)
Oiling-Out Crystallization of Beta-Alanine on Solid Surfaces Controlled by Solvent Exchange,
Advanced Materials Interfaces, DOI:
10.1002/admi.202001200.
Yang, H, Huang, L, Zhang, F, Karde, V, Yang, Z, Heng, JYY (2019)
Gravity on Crystallization of Lysozyme: Slower or Faster?,
Crystal Growth & Design, 19(12), pp.7402-7410, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.9b01447.
Yang, H, Belviso, BD, Li, X, Chen, W, Mastropietro, T, Di Profio, G, Caliandro, R, Heng, JYY (2019)
Optimization of vapor diffusion conditions for anti-CD20 crystallization and scale-up to meso batch,
Crystals, 9(5), DOI:
10.3390/cryst9050230.
Yang, H, Chen, W, Peczulis, P, Heng, JYY (2019)
Development and Workflow of a Continuous Protein Crystallization Process: A Case of Lysozyme,
Crystal Growth and Design, 19(2), pp.983-991, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.8b01534.
Yu, Q, Pu, J, Qi, M,
Yang, H (2019)
Jumping into metastable 1:1 urea-succinic acid cocrystal zone by freeze-drying,
Crystal Growth and Design, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.8b01778.
Yang, H, Zhang, F, Wu, H (2018)
Review on Life Cycle of Parabens: Synthesis, Degradation, Characterization and Safety Analysis,
Current Organic Chemistry, 22(8), pp.769-779, ISSN: 1385-2728. DOI:
10.2174/1385272822666180123150323.
Yang, H, Peczulis, P, Inguva, P, Li, X, Heng, JYY (2018)
Continuous protein crystallisation platform and process: Case of lysozyme,
Chemical Engineering Research and Design, 136, pp.529-535, ISSN: 0263-8762. DOI:
10.1016/j.cherd.2018.05.031.
Yang, H, Song, CL, Lim, YXS, Chen, W, Heng, JYY (2017)
Selective crystallisation of carbamazepine polymorphs on surfaces with differing properties,
CrystEngComm, 19(44), pp.6573-6578, DOI:
10.1039/c7ce01317e.
Yang, H and Florence, AJ (2017)
Relating induction time and metastable zone width,
CrystEngComm, 19(28), pp.3966-3978, DOI:
10.1039/c7ce00770a.
Yang, H, Yu, X, Raval, V, Makkawi, Y, Florence, A (2016)
Effect of Oscillatory Flow on Nucleation Kinetics of Butyl Paraben,
Crystal Growth & Design, 16(2), pp.875-886, ISSN: 1528-7483. DOI:
10.1021/acs.cgd.5b01437.
Bhardwaj, RM,
Yang, H, Florence, AJ (2016)
Crystal structure of the co-crystal butylparaben–isonicotinamide (1/1),
Acta Crystallographica Section E Crystallographic Communications, 72(1), pp.53-55, DOI:
10.1107/s2056989015023518.
Yang, H (2015)
Reply to the “Comment on ‘Relation between metastable zone width and induction time of butyl paraben in ethanol’” by L.-D. Shiau, CrystEngComm, 2015, 17, DOI: 10.1039/C5CE00101C,
CrystEngComm, 17(23), pp.4405-4407, DOI:
10.1039/c5ce00533g.
Yang, H (2015)
Relation between metastable zone width and induction time of butyl paraben in ethanol,
CrystEngComm, 17(3), pp.577-586, DOI:
10.1039/c4ce01625d.
Yang, H and Rasmuson, ÅC (2015)
Phase equilibrium and mechanisms of crystallization in liquid–liquid phase separating system,
Fluid Phase Equilibria, 385, pp.120-128, ISSN: 0378-3812. DOI:
10.1016/j.fluid.2014.11.007.
Yang, H, Svärd, M, Zeglinski, J, Rasmuson, ÅC (2014)
Influence of Solvent and Solid-State Structure on Nucleation of Parabens,
Crystal Growth & Design, 14(8), pp.3890-3902, ISSN: 1528-7483. DOI:
10.1021/cg500449d.
Yang, H and Rasmuson, ÅC (2014)
Ternary phase diagrams of ethyl paraben and propyl paraben in ethanol aqueous solvents,
Fluid Phase Equilibria, 376, pp.69-75, ISSN: 0378-3812. DOI:
10.1016/j.fluid.2014.05.036.
Yang, H, Chen, H, Rasmuson, ÅC (2014)
Sandwich crystals of butyl paraben,
CrystEngComm, 16(37), pp.8863-8873, DOI:
10.1039/c4ce01320d.
Yang, H and Rasmuson, ÅC (2013)
Nucleation of Butyl Paraben in Different Solvents,
Crystal Growth & Design, 13(10), pp.4226-4238, ISSN: 1528-7483. DOI:
10.1021/cg400177u.
Yang, H and Rasmuson, ÅC (2012)
Investigation of Batch Cooling Crystallization in a Liquid–Liquid Separating System by PAT,
Organic Process Research & Development, 16(6), pp.1212-1224, ISSN: 1083-6160. DOI:
10.1021/op200355b.
Yang, H, Thati, J, Rasmuson, ÅC (2012)
Thermodynamics of molecular solids in organic solvents,
The Journal of Chemical Thermodynamics, 48, pp.150-159, ISSN: 0021-9614. DOI:
10.1016/j.jct.2011.12.015.
Yang, H and Rasmuson, ÅC (2010)
Solubility of Butyl Paraben in Methanol, Ethanol, Propanol, Ethyl Acetate, Acetone, and Acetonitrile,
Journal of Chemical & Engineering Data, 55(11), pp.5091-5093, ISSN: 0021-9568. DOI:
10.1021/je1006289.
Dang, L,
Yang, H, Black, S, Wei, H (2009)
The Effect of Temperature and Solvent Composition on Transformation of β- to α-Glycine As Monitored in Situ by FBRM and PVM,
Organic Process Research & Development, 13(6), pp.1301-1306, ISSN: 1083-6160. DOI:
10.1021/op900134w.
